27-year-old Matthew Zahra has been reported missing, police said in a statement.
Zahra was last seen in Valletta and Marsaxlokk.
The man left his residence in Valletta on Wednesday 15 August and his car was found on Thursday in Marsaxlokk.
Zahra has dark brown hair and brown eyes.
The police said that anyone who has information on Zahra should call 119 or visit a police station.